About Help FAQ

Symbol
Name
ID

Pkhd1
polycystic kidney and hepatic disease 1
MGI:2155808

Phenotype annotations related to liver/biliary system

Darker colors indicate more annotations

Human Phenotypes

Portal hypertension

Hepatosplenomegaly

Hepatic fibrosis

Congenital hepatic fibrosis

Periportal fibrosis

Abnormal intrahepatic bile duct morphology

Biliary hyperplasia

Cholangiocarcinoma

Cholangitis

Cholestasis

Jaundice

Hepatoblastoma

Disease(s) Associated with PKHD1

autosomal recessive polycystic kidney disease

Mouse Phenotypes

abnormal cholangiocyte primary cilium morphology

hepatic necrosis

abnormal bile duct morphology

abnormal bile duct development

abnormal bile duct epithelium morphology

bile duct epithelium hyperplasia

abnormal extrahepatic bile duct morphology

abnormal hepatic duct morphology

abnormal intrahepatic bile duct morphology

bile duct hyperplasia

bile duct proliferation

biliary cyst

dilated bile duct

abnormal gallbladder morphology

liver cyst

enlarged liver

increased liver weight

bile duct inflammation

abnormal hepatobiliary system morphology

abnormal biliary tract morphology

abnormal liver development

abnormal liver morphology

liver fibrosis

Availability

Mouse Genotype

Pkhd1^cyli/Pkhd1^cyli

Pkhd1^em1Mrug/Pkhd1^em1Mrug

Pkhd1^tm1.1Ggg/Pkhd1^tm1.1Ggg

Pkhd1^tm1Cjwa/Pkhd1^tm1Cjwa

Pkhd1^tm1Gwu/Pkhd1^tm1Gwu

Pkhd1^tm1Rbu/Pkhd1^tm1Rbu

Pkhd1^tm1Som/Pkhd1^tm1Som

Pkhd1^tm1Sswi/Pkhd1^tm1Sswi

Pkhd1^tm2Cjwa/Pkhd1^tm2Cjwa

Pkhd1^em1Mrug/Pkhd1⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23